AgrA inhibitor F19
CAS No. 1532534-68-1
AgrA inhibitor F19 ( —— )
产品货号. M12157 CAS No. 1532534-68-1
AgrA inhibitor F19 is a small-molecule AgrA inhibitor that act as antivirulence agent against Gram-positive pathogens.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
100MG | 获取报价 | 有现货 |
|
200MG | 获取报价 | 有现货 |
|
500MG | 获取报价 | 有现货 |
|
1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称AgrA inhibitor F19
-
注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
-
产品简述AgrA inhibitor F19 is a small-molecule AgrA inhibitor that act as antivirulence agent against Gram-positive pathogens.
-
产品描述AgrA inhibitor F19 is a small-molecule AgrA inhibitor that act as antivirulence agent against Gram-positive pathogens, blocks staphylococcal transcription factor AgrA from binding to its promoter and inhibits toxin and virulence factor transcription; binds to C-terminal DNA-binding domain (AgrA_C) from Staphylococcus epidermidis with an affinity of 2.7 uM, potentiates β-lactam antibiotics in a MRSA wound model.
-
同义词——
-
通路GPCR/G Protein
-
靶点Antibacterial
-
受体Antibacterial
-
研究领域——
-
适应症——
化学信息
-
CAS Number1532534-68-1
-
分子量370.49
-
分子式C23H30O4
-
纯度>98% (HPLC)
-
溶解度——
-
SMILESCCCCCCC1=CC(=C(C=C1O)O)C(=O)COC2=CC=C(C=C2)C(C)C
-
化学全称1-(5-hexyl-2,4-dihydroxyphenyl)-2-(4-isopropylphenoxy)ethan-1-one
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Greenberg M, et al. Sci Rep. 2018 Oct 1;8(1):14578.
2. Khodaverdian V, et al. Antimicrob Agents Chemother. 2013 Aug;57(8):3645-52.
2. Khodaverdian V, et al. Antimicrob Agents Chemother. 2013 Aug;57(8):3645-52.
产品手册
关联产品
-
VNRX-5133
VNRX-5133 is a highly potent and specific beta-lactamase inhibitor.
-
Sulfometuron-methyl
Sulfometuron-methyl is a herbicide and also is an active antibacterial agent. It is an effective inhibitor of acetolactate synthase II and thus shows antibacterial properties.
-
Anhydrotetracycline ...
Anhydrotetracycline (hydrochloride) is a potent competitive inhibitor of broad-spectrum tetracycline destructase enzymes.