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AgrA inhibitor F19

CAS No. 1532534-68-1

AgrA inhibitor F19 ( —— )

产品货号. M12157 CAS No. 1532534-68-1

AgrA inhibitor F19 is a small-molecule AgrA inhibitor that act as antivirulence agent against Gram-positive pathogens.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    AgrA inhibitor F19
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    AgrA inhibitor F19 is a small-molecule AgrA inhibitor that act as antivirulence agent against Gram-positive pathogens.
  • 产品描述
    AgrA inhibitor F19 is a small-molecule AgrA inhibitor that act as antivirulence agent against Gram-positive pathogens, blocks staphylococcal transcription factor AgrA from binding to its promoter and inhibits toxin and virulence factor transcription; binds to C-terminal DNA-binding domain (AgrA_C) from Staphylococcus epidermidis with an affinity of 2.7 uM, potentiates β-lactam antibiotics in a MRSA wound model.
  • 同义词
    ——
  • 通路
    GPCR/G Protein
  • 靶点
    Antibacterial
  • 受体
    Antibacterial
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    1532534-68-1
  • 分子量
    370.49
  • 分子式
    C23H30O4
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    CCCCCCC1=CC(=C(C=C1O)O)C(=O)COC2=CC=C(C=C2)C(C)C
  • 化学全称
    1-(5-hexyl-2,4-dihydroxyphenyl)-2-(4-isopropylphenoxy)ethan-1-one

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Greenberg M, et al. Sci Rep. 2018 Oct 1;8(1):14578.
2. Khodaverdian V, et al. Antimicrob Agents Chemother. 2013 Aug;57(8):3645-52.
产品手册
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